National Institute for Medical Research (NIMR), Tanzania

Predicting the next epidemic: DHIS2-based risk modeling

Research project Unexpected onset of large-scale epidemics caused by climate-sensitive vector-borne diseases (VBDs) present a growing risk to human health and societal stability throughout the world. The situation is especially critical in LMICs as health systems str ...
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Green Resources Innovations For Livelihood Improvement

Research project The proposed collaborative project titled “Green Resources Innovations for Livelihood Improvement (GRILI)’ will be carried out in the Eastern Arc Mountains of Tanzania and Manyara region where Synadenium glaucescens, and Commiphora swynnertonii are f ... First-year report While the outcomes are not yet realized the results for specific objectives are: reconnaissance survey and the Inception meeting done involving 8 GRPs value chain actors and 7 stakeholders. 4 PhD students recruited on the areas ...
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Diabetes and associated complications in HIV patients

Research project The goal of the study is to generate data demonstrating that HIV patients have higher burden of diabetes in order to stimulate development of policies which will help optimize prevention and care of diabetes in HIV patients. Access to antiretro ... Midterm report Preliminary results show that of those recruited, 59% (1,157) were females and the mean age was 41 years. The overall prevalence of diabetes was 13% by glycated haemoglobin A1c (HbA1c) test and 6% by oral glucose tolerance test ...
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Development of malaria vaccines

Research project Malaria is responsible for an overwhelming disease burden and deployment of effective malaria vaccines would lead to major health gains, especially among most vulnerable groups: young children and pregnant women in rural areas. Tanzania and Denmark a ... Project completion report: The main aim and long term aim of this project was to develop new vaccines to malaria. The work proceeded along the normal rute for new medicinal products. The work was divided into a Discovery phase (discovery of new ...
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Operational research to support and enhance lymphatic filariasis control efforts in Eastern and Southern Africa

Research project Lymphatic filariasis (LF) is a disabling disease resulting from a mosquito-transmitted parasitic infection. It is one of the most prevalent of the Neglected Tropical Diseases, primarly a disease of the poor, and has recently been recognized by the W ... Completion Report - Summary: The project aimed to support LF control efforts in Zambia and Tanzania, through operational research and capacity building. Activities within the four work-packages started in 2010, with locally registered PhD and Mast ...
Period: 2009-12-31 to 2015-01-31 Countries: Tanzania Zambia Lead institution: University of Copenhagen (UCPH), Faculty of Health and Medical Sciences, Denmark Partner institutions: University of Copenhagen (UCPH), Denmark University of Zambia (UNZA), School of Veterinary Medicine, Zambia Project code: 09-096LIFE Total grant: 10,289,993 DKK
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Improving efficacy and safety of TB and HIV treatment by nutritional supplementation

Research project The two infectious diseases: Tuberculosis (TB) and HIV are closely linked with crowding, poverty and under-nutrition. The severe wasting seen with both diseases, and more so if co-infecting patients, may affect the absorption of drugs and conversion ... Completion Report - Summary: The prognosis of HIV-infected patients has improved dramatically in recent years but mortality remains high, particularly within the first few months of therapy. Malnutrition is a strong independent predictor of d ...
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Research and Capacity Building Related to Medicines for Major Health Problems in Tanzania (malaria, TB, and HIV)

Research project Effective drugs remain essential for the control of diseases like malaria and HIV where effective vaccines are not (yet) available; or when preventive measures alone may not be available, acceptable or practicable. New antiretroviral drugs (ARV) bec ... Project Completion Report: The project has built research capacity around use of medicines for major health problems in Tanzania: Malaria and HIV, and on how they may interact. A remark- able decline in malaria in the study area was found and ...
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Development of PfEMP1 based malaria vaccines

Research project PfEMP1 are a class of parasite proteins expressed on the surface of Plamosium falciparum-infected erythrocytes, where they function as adhesion receptors interacting with a range of host tissue ligands. Tissue adhesion of infected erythrocytes is a ... Project Completion Report: During this project we have: developed the first vaccine to protect women for pregnancy associated malaria planned to undergo clinical testing with the next years, defined the parasite proteins which precipitates se ...
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