Accelerating the development of a malaria vaccine for Africa

Malaria remains an internationally leading cause of ill health and poverty. There is no efficacious vaccine available, and recent progress in malaria control is jeopardized by drug resistance, failing…
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Functional Immuno-genetic Correlates of Immunity to Malaria

This project will define immune-genetic correlates of malaria immunity and strengthen research capacity through: 1. Identification of immuno-genetic determinants of immunity to malaria: Malaria…
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Malaria vaccine research and capacity building in Ghana

The applicants have previously collaborated successfully on malaria vaccine development, and have characterised a field site area prioritised by Ghana Health Services. This project builds on these…
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Assessment of the efficacy of a VAR2CSA based vaccine to prevent malaria in pregnant women

Malaria is the cause of severe maternal anaemia and is responsible for about one third of preventable low birth weight babies. It contributes to the deaths of an estimated 10,000 pregnant women and up…
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Development of PfEMP1 based malaria vaccines

PfEMP1 are a class of parasite proteins expressed on the surface of Plamosium falciparum-infected erythrocytes, where they function as adhesion receptors interacting with a range of host tissue…
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